AIMS Biophysics, 2021, 8(1): 34-40. doi: 10.3934/biophy.2021002

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Cold helium plasma as a modifier of free radical processes in the blood: in vitro study

1 Laboratory of Medical Biophysics, Privolzhsky Research Medical University, 603950, Nizhny Novgorod, Russia
2 Laboratory of Space Plasma Modeling, Institute of Applied Physics, 603950, Nizhny Novgorod, Russia
3 Department of animals’ physiology and biochemistry, Nizhny Novgorod State Agricultural Academy, 603107, Nizhny Novgorod, Russia
4 Bioniq Health-Tech Solutions, London, United Kingdom

We studied the influence of various exposures (1, 2, 3, 5, 10 and 15 min.) effects of cold helium plasma on the state of free radical processes in the biological fluid (human blood). It was found that the nature of the response of antioxidant systems of blood to cold plasma treatment is directly determined by exposure, as evidenced by the results of chemiluminescence assessment of the intensity of free radical processes and total antioxidant activity, as well as the dynamics of the concentration of malonic dialdehyde. At the same time, the short-term processing mode of biological fluid allows us to establish the presence of a two-phase influence of the factor on oxidative processes ( “the phenomenon of the antioxidant window” ).
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© 2021 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

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